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Higher doses (4.5 mg) were evaluated but discontinued due to excessive gastrointestinal side effects without proportional benefits[7]

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The images presented were deconvolved with a narrow Gaussian of 50 nm FWHM combined with a wider Gaussian of 175 nm FWHM accounting for 10% of the PSF amplitude, such a geometry considers the properties of rsFPs, where a background signal due to a non-photo-switchable fraction of the molecules is expected