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Identification of cytosolic leucyl aminopeptidase (EC 3.4.11.1) as the major cysteinylglycine hydrolysing activity in rat liver

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Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is an autosomal dominant disorder characterized by mutations in the FH gene that result in altered activity of fumarate hydratase, which is involved in the tricarboxylic acid cycle