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NaBPC157 was applied (10 ⁇ g or 10 ng/kg b.w., i.p.), either once daily for 28 days, or once daily for 14 days starting from the 15 th day post-ovariectomy

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However, upon binding to D -p53 TAD2 , several FOXO4-LRI residues shifted towards positive secondary chemical shifts, indicative for α-helix formation (Fig