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Even if cysteine S -conjugate β-lyase is responsible for the synthesis of the highly reactive and cytotoxic thiol version of cisplatin ( Figure 1 ), the activation of cisplatin into a nephrotoxin relies on the three previous steps of the classical mercapturic acid pathway involving GSTs (GSH conjugation), γGT (production of CisPt-cys-glu) and dipeptidase (production of CisPt-cys

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NovaGenix takes a balanced position: BPC-157 should not be promoted as a miracle treatment, but patients should not be frightened away from asking about it either